Bromelain for Post-surgery Facial Swelling
Purpose
The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol
Condition
- Malocclusion
Eligibility
- Eligible Ages
- Between 18 Years and 65 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- undergoing orthognathic surgery
Exclusion Criteria
- craniofacial anomalies - incomplete patient data - systemic disease that could affect healing - allergy to latex or pineapple - under 18 years of age - non english speaking
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Supportive Care
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Bromelain Supplement |
1000mg bromelain supplement once a day, 2 days prior to and 7 days following surgery |
|
|
No Intervention Control |
Standard of care |
|
Recruiting Locations
UK Center for Clinical and Translational Science and nearby locations
Lexington 4297983, Kentucky 6254925 40356
More Details
- NCT ID
- NCT07115212
- Status
- Recruiting
- Sponsor
- Mohamed Bazina